오론서 피네의 세계지도 연구: 하트 형태의 상징적 의미와 동아시아 정보를 중심으로

정인철 한국지도학회 2016 한국지도학회지 Vol.16 No.1

이 연구의 목적은 오론서 피네의 하트형 세계지도를 하트의 상징적 의미와 동아시아 정보의 관점에서 연구하는 것이다. 피네가 하트형 투영법을 채택한 이유로는 국왕 프랑수아 1세에 대한 충성을 표현하고 또 자신의 하트 기호에 대한 선호가 작용한 것으로 판명되었다. 지도속의 동아시아 정보는 아메리카와 아시아가 하나의 대륙으로 표기된 가운데, 마르코 폴로와 피가페타의 정보에 의존했음을 확인했다. 그리고 테라 오스트랄리스의 북쪽에 인도의 파탈리스 지역과 인도로 오인되는 남쪽의 브라질을 표기해, 16세기 디페 학파의 지도에서 대자바로 표기되는 근거를 제공했음을 알 수 있었다. The purpose of this paper is to explore Oronce Finé’s heart-shaped world maps in two aspects: symbolic meaning of heart-shape and East Asian information in the maps. Adopting cordiform map projection, Fine tried to present his royalty to the King Francine I and his love for heart sign. Representing Asia and North America as one continent, Fine drew East Asia based on Marco Polo and Pigafetta information. Patala region of India and Southern Brazil which may be interpreted as Indian region were marked in the northern part of Terra Australis, and this region was changed to Java la Grande in the Dieppe school of cartography.

HL-60 사람 백혈병 세포에서 irinotecan이 topoisomerase I과 DI의 활성과 발현에 미치는 영향

정인철,조무연 고신대학교(의대) 고신대학교 의과대학 학술지 2006 고신대학교 의과대학 학술지 Vol.21 No.1

Background DNA topois아nerases solve the topological problems associated with DNA replication, transcription, recombination, and chromatin remodeling by introducing temporary single- or double-strand breaks in the DNA. DNA topoisomerases have been shown to be the molecular targets of many antimicrobial and anticancer agents. Among topoisomerase- targeting drugs in clinical use at present, most act by trapping the covalent DNA-enzyme intermediates to convert a normal cellular enzyme to a DNA damaging agent. This studies were designed to elucidate whether pretreatment of HL-60 human leukemia cells with the topoisomerase I - directed drug irinotecan would increase the expression of topoisomerases and to investigate the activity of topoisomerase mediated by irinotecan in nuclear extract from HL-60 human leukemia cells. Methods We have conducted experiments on cell cytotoxicity in drug-treated HL-60 cells,topoisomerase purification, topoisomerase assay using gel electrophores and oligo chip microarray analysis,respectively. Results Irinotecan inhibited the relaxation activity of topoisomerase in pUC19 DNA at various concentrations (range 0.4-50 ᄍ M〉, Irinotecan IC(50) values was 1 uM for HL-60 cells. The levels of the topoisomerase Ktype IB) and IlKtype IA) mRNA remained no significant change from oligo chip microarray analysis. Conclusion Our results suggest that topoisomerase I protein is one of the cellular targets of irinotecan but this drug does not coordinate regulation with type I topoisomerase mRNA levels.

액체분무의 증발 및 연소에 관한 수치적 연구

정인철,이상용,백승욱 대한기계학회 1991 대한기계학회논문집 Vol.15 No.6

The vaporization and combustion of liquid spray in a cylindrical shape combustor was studied numerically. Mixture of liquid drops and air was assumed to be ejected from the center-hole and assisting air from the concentric annulus with swirling. Eulerian-Lagrangian scheme was adopted for the two phase calculation, and the interactions between the phases were considered with the PSIC model. Also adopted were the infinite conductivity model for drop vaporization, the equation of Arrhenius and the eddy break-up model for reaction rate, and the k-epsilon model for turbulence calculations. Gas flow patterns, drop trajectories and contours of temperature and mass fractions of the gas species were predicted with swirl number, drop diameter, and equivalence ratio taken as parameters. Calculations show that the vaporization and the consequent combustion efficiency enhance with the increase of the swirl number and/or with the decrease of drop size, and the higher maximum temperature is attained with the higher equivalence ratio.

HL-60 사람 백혈병 세포로부터 topoisomerase type 1B의 동정

정인철,곽충근,조무연 고신대학교(의대) 고신대학교 의과대학 학술지 2004 고신대학교 의과대학 학술지 Vol.19 No.1

Background : DNA topoisomerases fall into two categories -type 1 and type 2. For the type 1 enzymes, the DNA strands are transiently broken on at a time; for the type 2 enzymes, by contrast, a pair of strands in a DNA double helix are transiently broken in concert by a dimeric enzyme molecule. The two types can be further divided into four subfamilies: 1A, 1B, 2A and 2B. DNA topoisomerases solve the topological problems associated with DNA replication, transcription, recombination, and chromatin remodeling by introducing temporary single- or double-strand breaks in the DNA. Camptothecin is an antitumor alkaloid that has been isolated from the Chinese tree, Camptotheca acuminata. We have developed a procedure for the simultaneous purification of type 1 and 2 topoisomerase from HL-60 human leukemia cells, and identified type 1B topoisomerase. Methods : DNA topoisomerase was purified from HL-60 human leukemia cells by a simple and fast four-step procedure : seletive ammonium sulfate precipiation, chromatography on Ultrogel A6 and DNA- cellulose, followed by ultracentrifugation on a glycerol gradient. Enzyme activity, and molecular weight were assayed by measuring the relaxation of supercoiled pUC19 DNA using agarose gell elctrophoresis and sodium dodesyl sulfate denaturing gel electrophoresis, respectively. Results Type 1 and 2 topoisomerases were isolated from extracted nucleoprotein complexes by glycerol gradient centrifugation, respectively. Human type 1B topoisomerase was purified 8.6-fold as compared to the whole cell homogenate, with 12% yield. The purified type 1 topoisomerase has a molecular weight of 100 kDa as determined by SDS polyacrylamide gel electrophoresis. The enzyme relaxes supercoiled DNA in the absence of ATP or Mg2+. Camptothecin inhibited the relaxation activity of type 1 topoisomerase in pUC19 DNA by forming a cleavable complex at various concentrations (0.4-50 uM). Conclusion : The results showed that a type 1B topoisomerase has been purified to near homogeneity from HL-60 human leukemia cells, and partial purification of type 2A from small samples was achieved by isolation of cell nuclei. Thus, the potential antitumor activity of a type 1 and 2 topoisomerase-targeted drug might be easily screened by testing the drug's ability to cause DNA cleavage in the presence of enzymes.

[최종보고서] 대단위관광지 기본계획

정인철,김수봉,송부용,윤성윤,홍종욱,오건환,황창윤,곽태열,강혜정,서성욱,황인찬 경남발전연구원 1995 중점정책연구 기본연구 Vol.- No.-

Forward Link Performance of Pre-Rake TDD-CDMA systems with Multi-Antenna

정인철,이재영,Jeong, In-Cheol,Rhi, Jae-Young Korea Society of Satellite Technology 2011 한국위성정보통신학회논문지 Vol.11 No.2

저자는 참고문헌 [2]에서 복수의 송신안테나를 이용한 두 가지 Pre-Rake 송신다이버시티 방법 (system 1과 system 2)을 제안하였고 이론적인 해석과 컴퓨터 시뮬레이션을 통해 제안 시스템의 성능을 분석하였다. 그러나, 참고문헌 [2]에서는 전체 안테나를 이용하여 송신하는 system 2 에 대하여 다중사용자 환경을 고려한 성능 평가가 이루어지지 않았다. 따라서 본 논문에서는 다중사용자 환경에 대하여 system 2의 성능을 이론적으로 해석하고 한 개의 안테나를 선택하여 송신하는 system 1의 성능과 비교한다. 두 시스템의 성능평가 결과를 통해 사용자 수가 적을 때는 system 1이 좋은 성능을 보이며 사용자 수가 많아질수록 system 2가 system 1보다 좋은 성능을 나타내는 사실을 밝힌다. 이로써 사용자 수에 따라 Pre-Rake 송신다이버시티 타입을 기지국에서 선택하여 전송하는 것이 최상의 시스템 성능을 얻기 위해 필요함을 제시한다. The authors have proposed novel TDD-CDMA systems with Pre-Rake transmit diversity schemes (system 1 and system 2) using multiple transmit antennas in [2] and have also evaluated the system performance through the theoretical analysis and computer simulation. However, the performance of system 2 which transmit a signal using all antennas has not been evaluated for multi-user environment. Therefore in this paper, we analyze the performance of system 2 for multi-user environment and compare the performance with that of the already proposed system 1 which chooses only one antenna. From the numerical results, it is found that system 2 outperforms system 1 as the number of users increases while system 1 outperforms system 2 at a small number of users. Therefore in order to achieve the best system performance, the Pre-Rake transmit diversity type should be selected at the base station according to the number of users.

민들레 추출물 첨가가 돈육 Patty의 품질에 미치는 영향

정인철,박경숙 동아시아식생활학회 2015 동아시아식생활학회 학술발표대회논문집 Vol.2015 No.5

공간적 패턴클러스터링을 위한 새로운 접근방법의 제안 : 슈퍼마켓고객의 동선분석

정인철,권영식 대한산업공학회 2011 산업공학 Vol.24 No.4

Identifying the major moving patterns of shoppers' movements in the selling floor has been a longstanding issue in the retailing industry. With the advent of RFID technology, it has been easier to collect the moving data for a individual shopper's movement. Most of the previous studies used the traditional clustering technique to identify the major moving pattern of customers. However, in using clustering technique, due to the spatial constraint (aisle layout or other physical obstructions in the store), standard clustering methods are not feasible for moving data like shopping path should be adjusted for the analysis in advance, which is time-consuming and causes data distortion. To alleviate this problems, we propose a new approach to spatial pattern clustering based on longest common subsequence (LCSS). Experimental results using the real data obtained from a grocery in Seoul show that the proposed method performs well in finding the hot spot and dead spot as well as in finding the major path patterns of customer movements.

수세기를 통한 순열과 조합의 이해

정인철,Jung, In-Chul 영남수학회 2009 East Asian mathematical journal Vol.25 No.3

Permutation and combination are the part of mathematics which can be introduced the pliability and diversity of thought. In prior studies of permutation and combination, there treated difficulties of learning, strategy of problem solving, and errors that students might come up with. This paper provides the method so that meaningful teaching and learning might occur through the systematic approach of permutation and combination. But there were little prior studies treated counting numbers that basic of mathematics' action. Therefore this paper tries to help the understanding of permutation and combination with the process of changing from informal knowledge to formal knowledge.

도살체중이 돈육의 부위별 품질 및 기호성에 미치는 영향

정인철,박경숙,문윤희,Jung In-Chul,Park Kyung-Sook,Moon Yoon-Hee 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.1

The physicochemical properties and sensory characteristics for the neck, belly and ham of crossbred pigs SW90 (slaughter weight $90\sim100\;kg$) and SW110(slaughter weight $110\sim120\;kg$) were evaluated to investigate their quality. The water holding capacity, freezing loss, thawing loss, pan boiling loss and water boiling loss were not significantly different between SW90 and SW110, but the thawing loss and water boiling loss of belly were higher than those of other parts(p<0.05). The surface color was not affect by slaughter weight, but the L* value of belly was higher than that of the other parts and a* value was lower than that of the neck and ham(p<0.05). The mechanical texture was not affect by slaughter weight, the hardness of belly was lower than that of the neck and ham, but the springiness, cohesiveness, gumminess, chewiness and shear force of neck and ham were lower than those of belly(p<0.05). The pH, VBN content and TBARS value was not significantly different by slaughter weight. The taste, aroma, texture, juiciness and palatability of SW110 were higher than those of SW90, and the sensory characteristics of belly were higher than those of neck and ham, but their difference was not significant.