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- 저자 : Fen Ma (검색결과 17 건)
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Ma, Yong-Fen,Jung, Jae-Yeon,Jung, Yu-Jung,Choi, Ji-Hye,Jeong, Woo-Sik,Song, Young-Sun,Kang, Jae-Seon,Bi, Kaishun,Kim, Myo-Jeong The Korean Society of Food Science and Nutrition 2009 Preventive Nutrition and Food Science Vol.14 No.3
Five kinds of coumarin compounds were successfully purified from Angelica gigas Nakai by using recyclingpreparative HPLC and identified as decursin (1), decursinol angelate (2), 7-demethylsuberosine (3), marmesin (4), and decursinol (5) by NMR analyses. None of the purified compounds in ethanol showed DPPH radical scavenging activity, while the A. gigas extract (AGNEX) displayed a significant level of activity. Interestingly, compounds 3 in phosphate buffered saline (PBS) showed good $ABTS^+$ radical scavenging activity ($IC_{50}=8.1{\mu}g$/mL) as did compounds 4 and 5. The anti-inflammatory activities of the purified compounds were evaluated and compared using the NO concentration assay and western blot analysis on LPS-stimulated RAW 264.7 cells. NO production was significantly suppressed by all the compounds in a dose-dependent manner among which compounds 1, 2, and 3 showed very good activities with $IC_{50}$ values of 7.4, 6.5, and $7.6{\mu}g$/mL, respectively. Treatment with compounds 1-5 effectively suppressed the expression levels of iNOS, IL-1$\beta$, and COX-2, which are responsible for promoting the inflammatory process. Thus, the ethanol extract and coumarin compounds of A. gigas Nakai hold promise for use as potential anti-inflammatory agents.
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Design of Smart Tourism Data Mining Technology Based on Optimized Apriori Association Rule
Fen Ma Korean Institute of Information Scientists and Eng 2025 Journal of Computing Science and Engineering Vol.19 No.3
With the widespread application of information technology, smart tourism has emerged as an important direction for the development of the tourism industry. To improve the technological level of the smart tourism industry, a technology based on optimized Apriori association rule mining algorithm is designed. The Spark in-memory computing framework is chosen as the distributed programming framework to store elastic distributed datasets in distributed memory. The support is used to measure the probability of two scenic spots appearing simultaneously, and the order of tourists visiting the scenic spots is considered. A complete data mining process is designed. In the test of the association rules, the research method generated 4,271 association rules at a confidence level of 0.056. When the minimum support threshold of the research method was 30%, the number of invalid frequent itemsets generated was only 831. In the analysis of operational accuracy, the research method maintained an accuracy of over 98.8% when analyzing a data volume of 10,000. This indicates that the research method has good data mining performance and faster computation speed during runtime. The research method can provide good technical support for smart tourism.
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Evaluating optimum tilt angle for PV modules using solar radiation models in Wuhan, China
Fen. Li,Nianjun. Ma,Jinbin. Zhao,Keqing. Qu,Xingwu. Yang,Zhenghong. Chen 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
Four models are used to estimate the hourly solar radiation on 15 pieces of different tilted photovoltaic (PV) modules in Wuhan, China based on power and solar radiation data during a whole year. The optimum tilt angle (OTA) in Wuhan for yearly and semi-yearly adjustment was determined. Then it was determined that the best mode is the tilt angle of PV module adjusted every half a year. In semi-yearly adjustment, OTA in semi-year of winter and summer is found as 45°, 15°, respectively. Experimental results verify the theoretical calculated values of the OTA with high precision. Energy radio (ER) reveals PV modules with adjustment of tilt angle twice a year has a capability to improve nearly 7% in comparison with fixed type. The best model was chosen based on test results from statistical indicators. The statistical results demonstrate that among the studied models, Liu&Jordan model is the most accurate.
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Ling-fen Xu,Cheng Xu,Zhi-Qin Mao,Xu Teng,Li Ma,Mei Sun 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.2
To explore whether platelet-activating factor (PAF) can disrupt the intestinal epithelial barrier directly and is associated with structural alterations of the F-actin-based cytoskeleton, and to observe the protective effect of intestinal trefoil factor (ITF), we establish an intestinal epithelia barrier model using Caco-2 cells in vitro. Transepithelial electrical resistance and unidirectional flux of lucifer yellow were measured to evaluate barrier permeability; immunofluorescent staining and flow cytometry were applied to observe morphological alterations and to quantify proteins of the F-actin cytoskeleton: the tight junction marker ZO-1 and Claudin-1 were observed using immunofluorescent staining. PAF significantly increased paracellular permeability, at the same time, F-actin and tight junction proteins were disrupted. It was thought that ITF could reverse the high permeability by restoring normal F-actin, ZO-1 and Claudin-1 structures. These results collectively demonstrated that PAF plays an important role in the regulation of mucosal permeability and the effects of PAF are correlated with structural alterations of the F-actin-based cytoskeleton and of tight junctions. ITF can protect intestinal epithelium against PAF-induced disruption by restricting the rearrangement of the F-actin cytoskeleton and of tight junctions.
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The Effect of Adapted Aquatic Activity for Children with Cerebral Palsy in School Age
( Xiaohui Hou ),( Yanqing Fen ),( Zeming Ma ),( Hanjing ),( Yuedan Wu ),( Xiaodong Tian ) 한국체육학회 2015 국제스포츠과학 학술대회 Vol.2015 No.1
Objective: To observe the effect of adapted aquatic activity in the role of rehabilitation for children with cerebral palsy in school age. Methods: Twenty-four spastic cerebral palsy children of Guangzhou Cerebral Palsy Rehabilitation School were selected as subjects. These subjects were divided into the control group (regular rehabilitation therapy, RRT, n=12) and the experimental group (regular rehabilitation plus adapted aquatic activity with Halliwick technique, APA n=12). GMFM-88, the Berg balance scale, BMI and sit and reach were measured before and after the treatment. Results: After treatment, GMFM-88 total scores, Berg Balance Scale scores ,Lung`s capacity, sit and reach of APA group increased significantly than before, P<0.05. The RRT group increased too, but the difference was not significant. Half of experiment group can swimming 50-100m independently after 4 months training. There was no significant difference of BMI, sit and reach,GMFM-88 total scores, Berg Balance Scale scores between two groups after treatment (P>0.05), except lung`s capacity of APA group was significant higher than the control group (P < 0.05). Conclusion: Halliwick technical is an effective method to guide APA for school-aged children with cerebral palsy. APA can effectively enhance the gross motor function, balance, flexibility and respiratory capacity and it could be an effective method with other method for school-aged children with cerebral palsy to achieve life-long sport and rehabilitation. But how long to achieve significant effect still need to more research.
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Chaomin Yin,Xiuzhi Fan,Kun Ma,Zheya Chen,Defang Shi,Fen Yao,Hong Gao,Aimin Ma 한국미생물학회 2020 The journal of microbiology Vol.58 No.1
A lectin gene (plectin) with a high level of expression was previously identified by comparative transcriptome analysis of Pleurotus ostreatus. In this study, we cloned a 733-bp DNA fragment from the start codon of the plectin gene. Sequence analysis showed that the plectin promoter (Plp) region contained several eukaryotic transcription factor binding motifs, such as the TATA-box, four possible CAAT-box, light responsiveness motifs and MeJA-responsiveness motifs. To determine whether the Plp promoter was a light-regulated promoter, we constructed an expression vector with the fused egfp-hph fragment under the control of the Plp promoter and transformed P. ostreatus mycelia via Agrobacterium tumefaciens. PCR and Southern blot analyses confirmed the Plpegfp- hph fragment was integrated into the chromosomal DNA of transformants. qRT-PCR, egfp visualization, and intracellular egfp determination experiments showed the Plp promoter could be a light-induced promoter that may be suitable for P. ostreatus genetic engineering. This study lays the foundation for gene homologous expression in P. ostreatus.
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Huixian Chen,Yi Fang,Linlin Ma,Wen Jiang,Fen Luo,Shuya Cai,Zhi Li,Liyan Fu,Zhiqin Yin 한국간호과학회 2025 Asian Nursing Research Vol.19 No.1
Purpose: This study aims to explore the relationships between gestational diabetes mellitus (GDM)-related breastfeeding knowledge, GDM-related breastfeeding health beliefs, and breastfeeding intention. It investigates the factors influencing breastfeeding intention among pregnant women in Nepal. Methods: A total of 229 healthy pregnant women visiting an antenatal clinic in Nepal participated in thisstudy between January and March, 2023. They completed a questionnaire that assessed their GDMrelatedbreastfeeding knowledge, GDM-related breastfeeding health beliefs, and breastfeeding intention. The data were analyzed using descriptive statistics, an independent t-test, one-way analysis ofvariance including Scheff e’s post hoc test, and logistic regression analysis. Results: Of the participants, 86.9% (n ¼ 199) indicated positive breastfeeding intention, even with arelatively low level of GDM-related breastfeeding knowledge. Logistic regression analysis of the factorsinfluencing breastfeeding intention yielded a significant model (c2 ¼ 38.80, p < .001) with significantvariables; GDM-related breastfeeding knowledge [odds ratio (OR): 1.0, 95% confidence interval (CI): 1.02e1.40], GDM-related breastfeeding health beliefs (OR: 1.09, 95% CI: 1.04e1.15), and immediate familyexperience with diabetes mellitus (OR: 5.38, 95% CI: 1.98e14.62). Conclusion: Nurses should lead interventions to educate pregnant women about the benefits ofbreastfeeding that can help in mitigating the long-term effects of GDM and reinforce health beliefsthrough positive experiences. This study provides information demonstrating the need for nurse-ledimprovements in Nepal's GDM management system, from screening to comprehensive care.
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