Cadmium으로부터 유도된 HaCaT 각질형성세포 손상에 대한 Fucoxanthin의 세포보호효과

김보애 케이뷰티인학회 2026 케이뷰티인학회지 Vol.6 No.2

This study evaluated the protective effect of fucoxanthin on keratinocytes after inducing cell damage with the heavy metal cadmium. First, cell viability was measured by treating keratinocytes with fucoxanthin at concentrations of 5, 10, 20, 40, and 80 μM. The group treated with 80 μM showed a low viability of 78.32%, so 40 μM was selected as the highest treat ment concentration. The group treated with 100 μM of cadmium showed a cell viability of 58.71%, while cell viability re covered to 82.32% when pretreated with 40 μM of fucoxanthin. In the case of PGE2 (prostaglandin E2), the group treated with 100 μM of cadmium increased by 194.57% compared to the control group, while treatment with fucoxanthin de creased by 27.64%. As a result of testing COX-2(cyclooxygenase-2) expression, it decreased by 0.5 in the group treated with 40 μM fucoxanthin compared to the group treated with cadmium alone. These results suggest that fucoxanthin pro tects skin keratinocytes from heavy metals.

『그 후(それから)』에 나타난 다이스케(代助)의 내적불안 고찰

김보애 한국일본어문학회 2014 일본어문학 Vol.63 No.-

Soseki Natsume(1867-1916)'s biography in three parts 『Sansiro』『After that』 『Door』 had been serialized on 「Asahi daily news」 side by side for three years during 1908 to 1910, each character thereof had common connectivity. Because the background of the works described anxious psychology of the characters who were in the situation of disordered latter part of Meiji just after Russo-Japanese Wars. 『After that』 described the main character, Daisuke's anxiety, who lived as an educated idlerein Meiji era after Russo-Japanese Wars, as the figure of the nature such as flower, rain, wind, etc. symbolically. Lacans said, Anxiety never deceives us”. Daisuke's life, who was the beneficiary of culture, showed aristocratic composure, however the reader can grasp in the space between the lines that his self who was anxious in the society of Meiji era, although he acted out gentility by himself. His anxiety is maximized in unconsciousness. Daisuke was an educated idler,who was free intellectual rake, however he was suppressed by his father who was grasped by the typical Meiji country view and money view, among such idleness, also, was suppressed by unreasonable society and desire for his friend's wife. The anxiety was colored in red, and described as flower scent or sensuous expressions about the nature in unconsciousness. This research investigated Daisuke's anxiety in『After that』, the symbol and reason thereof.

블루라이트 차단 효과 평가를 위한 동물대체시험 모델의 응용: 제브라피쉬 모델을 중심으로

김보애 목원대학교 교양교육혁신연구센터 2023 지식과 교양 Vol.- No.12

Blue light has a wavelength of 400 to 500 nm and is widely recognized as a cause of harm to skin health in modern society where the use of electronic devices emitting blue light is common. In this study, an alternative animal model is introduced as a way to characterize the blue light blocking effect. Based on a theoretical background, blue light was irradiated to zebrafish from the embryo stage, and then the degree of melanin formation was observed to investigate the potential of the new research method. As a result, the blue light irradiation group showed a high pigmentation rate at 12 and 24 hpf. In the experimental group irradiated with fluorescent light, the pigmentation rate was 54% lower than that of the blue light irradiated group. The fluorescent light and negative control group, the light-shielded experimental group, had a lower melanin pigmentation rate than the fluorescent light and blue light irradiation groups. Whitening research using zebrafish has the advantage of simultaneously testing toxicity and whitening, making it a highly efficient evaluation method and thus highly likely to be used in the cosmetics industry as an in vivo experimental model that can replace existing animal experiments.

한국 조리직 종사자의 산재사고 및 직업성 질병 특성

김보애,이유진 (사)한국직업건강간호협회 2023 직업건강연구 Vol.5 No.3

Purpose : The present study aimed to compare and analyze the characteristics of occupational injuries and illnesses among cooking workers with those in other occupations. Methods : Analyzing 1,001,731 occupational accidents from 2013 to 2022, we categorized occupations into cooking workers and other occupations. Descriptive statistics, χ2 analysis, and charts were used to analyze the differences using SAS 9.4. Results : Cooking workers, primarily consisted of elderly females in small-scale establishments with fewer than 5 employees, showed a higher prevalence of incidents such as falls, musculoskeletal disorders, and burns. Challenges persist, particularly regarding unresolved issues and heightened anxiety related to occupational cancer recognition, leading to job turnover. Conclusion : Consequently, addressing various contributing factors to occupational incidents among cooking workers requires a preventive approach with complex intervention strategies rather than simple causal analysis.

파라벤 보존제의 안전성에 대한 고찰

김보애 한국소비자안전학회 2024 한국소비자안전학회지 Vol.9 No.1

Paraben is a preservative used in various fields such as cosmetics, food, and medicine. It has excellent antibacterial effects even at low concentrations, so it plays a role in preventing spoilage of various products. However, due to research results showing that it has hormonal disruption, reproductive toxicity, and genotoxicity, it is a reality that it is avoided as a preservative used in humans. For decades, parabens were considered very safe for living organisms, but recently, many research results have been published that refute this. However, this does not mean that preservatives that replace parabens are safe. Various controversies about parabens are not finding a consensus from various perspectives. This study aims to examine various research results and various perspectives on parabens.

라디오방송 텍스트의 정보조정에 관한 연구 -NHK World JAPAN ‘이야기로 즐기는 일본의 미’의 사례에서-

김보애 동아시아일본학회 2019 일본문화연구 Vol.0 No.71

This study concentrated on a program introducing ‘Fumie’ in ‘The Magic of Japanese Masterpieces’ that is a radio broadcasting of the NHK World JAPAN and examined a method to adjust information with texts of radio broadcasting in the course of delivering the Japanese culture to public after translating it into Korean that is a foreign language through the radio media. The above radio broadcasting is a program that is broadcasted with the 17 foreign languages based on the English script that was translated from an original Japanese manuscript. In results of analysis on the texts after transcribing the Korean broadcasting, several interesting facts were observed in a way of adjusting information. When broadcasting the Japanese culture using the Korean language, it was observed that some strategies, for instance, a strategy of using hypernym, a strategy of adding information, and a strategy of supplementing additional information on top of existing information were applied in the part that seemed to adjust the information before broadcasting it for the Korean radio audience with Korean language. Through a case study of ‘The Magic of Japanese Masterpieces’, those strategies, reversely, will be some references for the radio texts to deliver the Korean culture with the Japanese language and other texts.

서울시립동부아동상담소 사례 : 약물 남용 청소년들에 대한 기입

김보애 한국마약범죄학회 1999 마약범죄연구 Vol.4 No.-

피학대 청소년의 모래놀이치료 사례연구

김보애 한국아동심리재활학회 2004 놀이치료연구 Vol.8 No.1

Sandplay therapy was originated by Kalff who associated Jungian theory, the process of individuation with Lowenfeld's 'The World Technique'. Kalff developed sandplay therapy as knowing Jung through Lowenfeld. Sandplay therapy encourages us to discover potentials from the unconsciousness. In this process, we are able to accept ourselves as we are and experience the process of individuation as the way of becoming a whole being. Since Sandplay therapy uses a method, called 'experiencing symbols in the protective setting', without verbal expressions and there is no needs of interpreting the meanings of symbols, it is useful for clients with the lack of verbal expressions. Even therapy can be effective when the clients are not talked what symbols mean. For children, it can be useful for clients who have difficulties in verbal expressions or avoid to talk. Because Sandplay therapy makes it possible to communicate nonverbal, it is helpful to understand the adolescents who have difficulties in expressing inner selves. This study shows a case of a neglected adolescent with who performs 20 sessions of sandplay therapy. Although this girl had been very violent and a leader in peer group, she showed a great progress and got more involved in community after receiving the therapy. She intended to change and begin a new life. 모래놀이치료는 ‘세계기법’을 창시한 로웬펠드를 융으로부터 소개받은 칼프가 발전시킨 것으로, 칼프는 로웬펠드의 방법을 융의 개성화 이론과 연계시켜 모래놀이치료로 발전시켰다. 모래놀이를 통해 인간은 자신의 무의식층에 있는 무한한 가능성을 의식으로 끌어올림으로써 통합되어가고, 이로써 인간은 온전한 인간으로 본래의 자기의 모습으로 있는 그대로 실현하는 개성화 과정을 거치게 된다. 모래놀이치료는 내담자가 언어를 수단으로 하지 않고 ‘보호된 장면에서의 상징체험’에 의하여 치료가 진행되어 가기에, 그리고 상징이 의미하는 것을 굳이 해석해서 내담자에게 전하지 않더라도 치료가 되고 아동의 경우는 아무런 해석도 필요하지 않기에 언어적 표현이 부족하거나 말하는 것을 싫어하는 내담자에게 유용한 심리치료법이다. 또한 사춘기 청소년들의 경우 자기의 내적 체험을 언어적으로 표현하는 것이 거의 불가능하기에 모래상자라는 비언어적인 의사소통의 장을 제공해 줌으로써 지금까지 이해가 제대로 되지 않아서 곤란했던 사춘기 청소년들에게 도움이 되고 있다. 본 연구는 부모로부터 방임되어 온 청소년에 대한 사례로 폭력적인 특성을 갖고 있는 청소년에게 총 20회의 모래놀이치료로 개입한 과정을 다루고 있다. 본 사례의 청소년은 또래들 사이에서 리더적인 역할을 하며 폭력을 행사하였으나 치료를 받으면서 점차적으로 집단에 적응하고 안정되어 가는 모습을 보였으며 새롭게 출발하고자 하는 의지를 보이는 변화를 갖게 되었다.

바이오 융합기술과 화장품

김보애 한국문화융합학회 2018 한국문화융합학회 전국학술대회 Vol.2018 No.6

천연유래 소재를 이용한 화장품 연구개발

김보애 한국문화융합학회 2018 한국문화융합학회 전국학술대회 Vol.2018 No.6